Mohammad Abbas ripped through Pakistan to claim his first 10-wicket Test haul as Australia crumbled to a crushing 373-run defeat and a series loss in Abu Dhabi on day four.
Abbas has been the scourge of Australia in the United Arab Emirates, taking seven wickets in a drawn first Test and bowling Pakistan to victory with match figures of 10-95 at Sheikh Zayed Stadium.
The seamer took 5-62 on Friday as the tourists were skittled out for only 164, failing to produce another great escape after salvaging an unlikely draw in Dubai last week.
Asad Shafiq captained Pakistan in the absence of Sarfraz Ahmed, who was taken to hospital for a check-up after being struck on the helmet while batting on day three but was cleared to watch his team-mates seal an emphatic win.
Australia were indebted to Usman Khawaja after he scored a brilliant defiant century in Dubai, but the opener was unable to bat on the penultimate day due to a knee injury that requires surgery and could keep him out of the home series against India.
Marnus Labuschagne top scored with 43 for Tim Paine's side, but Abbas and Yasir Shah (3-45) made light work of wrapping up a triumph that pushes Australia down to fifth in the rankings.
Australia's slim hopes of thwarting Pakistan again all-but disappeared in quick time after they resumed on 47/1, Abbas doing the damage in a magnificent spell.
The seamer ended a second-wicket stand of 61 by tempting Travis Head (36) to fish outside the off stump, stand-in wicketkeeper Mohammad Rizwan taking the catch.
Mitchell Marsh failed for the fourth time in the series, Abbas getting one to nip back in and trap the all-rounder leg following a review after Richard Illingworth initially decided against raising the finger.
Aaron Finch (31) added just seven runs to his overnight tally before he fell in the same fashion during the next over from the brilliant Abbas.
Paine became Abbas' fourth victim, shouldering arms to a ball that jagged back in off the seam, reducing a teetering Australia to 78-5.
Mitchell Starc and Labuschagne offered some resistance with a partnership of 67, but Yasir snared the paceman lbw and Peter Siddle soon followed when he was struck in front with lunch looming.
Lyon would also have been on his way if Pakistan had reviewed when he was rapped on the pads by a full-length delivery from Yasir in the first over after lunch, but that was never likely to be costly.
Abbas had a fifth wicket when Labuschagne was caught behind on the hook and Yasir punched the air after Jon Holland edged him to Haris Sohail at second slip to end the match early in the afternoon session.
|Home sweet home for Wozniacki as Stephens conquers Melbourne demons|
|Nadal: Victory over Ebden a step forward|
|Proteas rest Steyn and De Kock for opening ODIs|
|Nadal and Federer march on as rising stars prosper|
|Barcelona president Bartomeu convinced Valverde will stay|
|Inter forward Keita suffers thigh injury|
|Nadal races into third round with easy Ebden win|
|Kimmich ´perfect´ for Barcelona, says Xavi|
|Richardson and Nabi inspire Renegades´ rout of Sixers|
|This Liverpool isn´t a team of chokers – Mane|
|Central Coast Mariners 2 Melbourne City 1: Late Simon winner ends 10-match losing streak|
|Bryan backs Murray to return after hip resurfacing surgery|
|Scotland coach Townsend turns to trio of uncapped hookers|
|Spurs´ Aurier arrested on suspicion of assault, released without charge|
|That was a fireworks show - Warriors revel in record-breaking first quarter|
|We are in talks with Chelsea – Salihamidzic reiterates interest in Hudson-Odoi|
|´Proud´ Messi recognises impact of team-mates after reaching 400 LaLiga goals|
|Henry v Vieira: The Arsene Wenger proteges to move into coaching|
|Federer enjoys ´cat and mouse´ win over Evans|
|Wozniacki cruises through in Melbourne|
|Federer maintains perfect Australian Open second-round record|
|Warriors set NBA record, Butler´s 76ers rout Timberwolves|
|´I like the fact we beat them´ - 76ers´ Butler revels in win over Timberwolves|
|Murray says he´ll ´probably´ have operation|
|Australian Open tribute for Andy Murray surprises brother Jamie|
|Warriors score NBA record 51 points in first quarter against Nuggets|
|Panthers owner Tepper doesn´t rule out Newton missing 2019 because of shoulder injury|
|De Ligt will be world´s best centre-back – Koeman|
|Ronaldo a ´perfect machine´, says Gattuso|
|Barcelona? I can´t say anything - Stuani|
|Silva upbeat about Man City title chances|
|Celtics youngsters say Irving´s callout ´came from a good place´|
|NFL playoffs: Patrick Mahomes v Tom Brady|
|NFL playoffs: Jared Goff v Drew Brees|
|Sixers sign Brewer to 10-day contract|
|Lozano and Morgan scoop CONCACAF awards|
|Lakers ´optimistic´ about LeBron injury|
|Giants produce mammoth fourth quarter against Nymburk|
|Austin FC to join MLS in 2021|
|Henry, Vieira look forward to reunion when Monaco host Nice|
|Barcelona reject Neymar phone call reports|
|Wentz is the quarterback ´going forward´, says Eagles coach Pederson|
|Gattuso: Higuain has not asked to leave|
|Drew Brees by the Opta numbers: 10 facts for QB´s milestone birthday|
|Harry Kane injury: England captain´s history of ankle woe|
|Harry Kane injury: Opta numbers suggest Spurs struggles|
|Harry Kane injury: Tottenham´s options in striker´s absence|
|Allegri: Supercoppa clash practice for Champions League knockouts|
|First in clean sheets, second to Schmeichel in titles – Cech´s Premier League career in Opta numbers|
|Warrington sign England star Widdop|
|Gatland confident Wales can win Six Nations|
|Fulham sign Netherlands international Babel|
|Harry Kane injury: Games the Tottenham striker will miss|
|Simeone focused on matches, not transfer dealings|
|Iran v Iraq: Pressure off for Queiroz & Katanec|
|Vietnam v Yemen: Kocian keeps the faith|
|Darren Bravo back in West Indies Test side for first time since 2016|
|Kane out until March with ankle injury|
|South Korea v China: Son arrives for Group C dead rubber|
|Kyrgyzstan v Philippines: Eriksson remains hopeful|
|McGrath to miss Six Nations, Sexton nearing fitness|
|Kohli savours Dhoni ´classic´|
|Ford: People obsess over Farrell fly-half battle|
|EFL asks Leeds to explain ´spygate´ scandal|
|No alarms for Djokovic and Zverev, Raonic masters Kyrgios|
|Australia 3 Syria 2: Rogic breaks hearts with stoppage-time winner|
|Palestine 0 Jordan 0: Socceroos winner keeps hopes alive for Lions of Canaan|
|Halep: The results don´t matter any more|
|Hard work for Halep as Serena and Osaka sail through|
|Napoli director to take legal action over ´false´ quotes about Rog move|